I've Modded my ASUS P8P67 Deluxe 2001 BIOS with a Intel Raid Option Rom11.0.0.1124  & also updated the ME Firmware to 7.1.20.1119. While I was in there I've done the JMicron_JMB362_OptionROM_v1.07.28 as well. I used AMI Aptio MMTool 4.50.0.23 to replace the opt roms and the FWUpdLcl.exe in dos mode to flash the ME firmware.

Now lets move along to Overclocking to 4.5GHz , I'm using a water cooled set up so all is looking well.

I'm using Corsair CORSAIR DOMINATOR GT 8GB (2x 4GB) ultra-high performance memory module kit , 2000MHz, 9-10-9-27 CMT8GX3M2A2000C9. So your DRAM settings will be different. Just set your module to specs. I have my CAS timings on these modules @ 9-11-10-28  1T.  @1.65v @ 2133MHz

Enable all C States..

That is all your major changes for the Overclock , set the rest of your system up to your liking..